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4 When hearing of carotenoids, many people think of bright orange or red vegetables such as carrots or tomatoes

They often function as physiological regulators of intracellular signaling pathways, mediate the redox modifications of proteins, and function as intracellular messengers, all crucial roles in the human body

9.6 GSH-depletion mediated cancer therapy Reducing intracellular GSH levels enhances reactive oxygen species (ROS)-based therapies by weakening the cells antioxidant protection mechanisms Fig