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Chronic activation of these glial cells drives neuroinflammatory processes that accelerate neurodegeneration, making their modulation a critical therapeutic target

Participants who stayed on treatment throughout the study achieved an average of ~17% weight loss

But it might not be worth it for everyone

With GLP-1s shrinking appetite, there are even fewer opportunities to hit that goal making fiber an even higher priority

The peptide activates tissue remodeling through stimulation of decorin, which organizes collagen fibril architecture, and through suppression of transforming growth factor-beta (TGF-) signaling, reducing fibrotic scar formation [3]