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They are becoming super trendy

Hyeon-Cheol Lee-Okada and Takehiko Yokomizo, Juntendo University

BPC-157 is among the peptides that have drawn regulatory scrutiny because it has not undergone the FDA's drug approval process, meaning its risks and benefits have not been established through the rigorous clinical trials required for approved medications

Persistent Opioid Use After Hospital Admission From Surgery in New Zealand: A Population-Based Study Anesth Analg 2024;139:70110) Outcomes Related to New Persistent Opioid Use After Surgery or Trauma A Population-based Cohort Study (Ann Surg 2025;281:354360) IF YOU DONT MEASURE YOU CANT IMPROVE

It is important to understand that while improving gut barrier function is increasingly used in the clinical setting as a therapeutic goal, the evidence is not yet there to support the efficacy of a single intervention in curing a disease by restoring or improving barrier function