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Also, a substantial decrease in glutathione levels precedes the mitochondrial dysfunction and neuronal death found in Parkinsons disease, suggesting GSH depletion may initiate the subsequent impairment.It also suggests that increasing GSH levels may have potential benefit toward preventing diseases associated with mitochondrial dysfunction

Mol Biol Rep 2014;41(6):3867-3879

Diperbarui pada 18 Februari 2026

Certain foods can support natural glutathione production, such as citrus fruits, spinach and broccoli, and nuts and seeds

A purified wheat glutathione synthetase (GSH-S) showed no activity against L-serine or D-serine though low activity was reported against certain other L- and D-amino acids as well as glycine (Skipsey et al., 2005a)