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Understanding the current evidence, acknowledging the limitations, and consulting with knowledgeable healthcare providers are all important steps

The oncogenic role of D-2HG is mainly driven by its inhibition of the KG-dependent dioxygenases and, consequently, a broad epigenetic resetting typical for IDH-mutated tumors [77]

Ribose-5-phosphate is a precursor for ribonucleic acids required for cell growth, proliferation, and transcription