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Thus, designing an all-rounder with space-time ROS scavenging, modulation of macrophage polarization, and promotion of angiogenesis and cell proliferation is a prominent subject for advancing the clinical treatment of chronic diabetic wounds

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Tissue effects (angiogenesis, VEGF-receptor signaling, growth factor cross-talk) persist much longer than the plasma window

However, the underlying mechanism remains to be explored

(4) The peptide was suggested to significantly lower ROS levels, unlike higher concentrations that did not demonstrate similar protective actions