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Alternative OPPS Policies Considered Alternatives to the OPPS changes we proposed and the reasons for our selected alternatives are discussed throughout this final rule with comment period

Vitamin C in its ascorbic acid form is a notable example

This is a custom-compounded injectable formulation combining two active ingredients: Semaglutide a GLP-1 receptor agonist known for appetite suppression, improved glucose control, and weight loss effects Empower Pharmacy+1 Cyanocobalamin a version of vitamin B12, important for energy metabolism, neurological function, and red blood cell production Empower Pharmacy+2Wikipedia+2 Empower Pharmacy produces this injectable under their compounding operations and offers it through their 503A compounding pharmacy (patient-specific prescriptions) and 503B facility for larger sterile compounding needs Empower Pharmacy+3Empower Pharmacy+3Empower Pharmacy+3 Because its a compounded product, it is not FDA-approved as a branded drug