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GH Secretagogue Comparison Compound Class Receptor FDA Status Ipamorelin GHRP (ghrelin mimetic) GHS-R1a Not approved CJC-1295 GHRH analog GHRH-R Not approved Sermorelin GHRH analog GHRH-R Previously approved (Geref, discontinued) Tesamorelin GHRH analog GHRH-R FDA approved (Egrifta) GHRP-2 GHRP (ghrelin mimetic) GHS-R1a Not approved GHRP-6 GHRP (ghrelin mimetic) GHS-R1a Not approved Selectivity Profile: The Key Research Differentiator What makes Ipamorelin stand out among GHRPs is its endocrine selectivity

As it works, GSH is converted into GSSG, the oxidized form, which your body can recycle back into GSH to maintain antioxidant protection

In experimental models, Ipamorelin has been investigated for its ability to interact with growth hormone secretagogue receptors (GHSR), which are involved in regulating growth hormone signaling within the body

doi: 10.1111/j.1365-2605.2005.00598.x 31 DuttaSSenguptaPRoychoudhurySChakravarthiSWangCWSlamaP

There is no evidence-based dosing guidance for CJC-1295