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Dose adjustments may be necessary if gastrointestinal side effects become problematic

Gut 2005;54:1782-9

We see it across a range of conditions but the real standout is with respect to opioid overdoses, where the rate of opioid overdose deaths for people right after they leave prison or jail is significantly higher than it is for the population as a whole. The idea behind this waiver is to mitigate the coverage gap for individuals leaving prison and ensure a better continuum of care

Lifestyle interventions including adequate protein intake, resistance exercise, sleep optimisation, and alcohol reduction are evidence-based complements to weight-loss pharmacotherapy