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Dependiendo de la estructura del ligando, se modulan las vas de sealizacin intracelular hacia la generacin de AMP cclico, cascada de activacin de quinasas (ERK) y reclutamiento de beta arrestina-1 que condiciona el efecto biolgico y la desensibilizacin del receptor de GLP-14

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Compounded semaglutide can offer advantages over brand name medications, such as customized formulations and potentially wider availability, and also allow for personalized dosing adjustments

BMJ 2016;355:I4919