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These may occur if: The injection was too shallow or too deep The fluid volume was too high for the site The product was too concentrated or acidic Local immune cells formed a small granuloma (harmless but annoying) Applying a warm compress can help disperse the fluid and reduce the lump

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A review of the toxicity of HIV medications

doi:10.1007/s11064-012-0895-x Lin JB, Apte RS