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These devices can be used for various therapies, such as intracavernosal injections for erectile dysfunction, weight loss medications (GLP-1s like semaglutide), and testosterone or hormone replacement therapy

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Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition