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Chronic Ex-4 treatment To test whether chronic icv administration of Ex-4 alters autonomic nervous system activity, we administered icv Ex-4 (10 ng/h) continuously during a 28 day period

327 This cascade induces intracellular Ca 2+ mobilization, ultimately leading to vascular smooth muscle contraction and increased systemic vascular resistance

Resumen de investigacin preclnica Remodelacin tisular y biologa de la matriz extracelular Diversas investigaciones preclnicas han examinado el papel del complejo GHK-Cu en modelos experimentales relacionados con la regulacin de la matriz extracelular y la remodelacin tisular