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Trial data from STEP 4 (semaglutide) and SURMOUNT-4 (tirzepatide) show most of the weight is regained over 5288 weeks after discontinuation

This assay is widely used for immunogenicity testing of GLP-1 analog drugs

In knockdown experiment, HUV-EC-C, a cell line of HUVECs, was used

It significantly ameliorates high-fat diet-induced structural dysbiosis of the gut microbiota by reducing the abundance of harmful bacteria positively correlated with hepatic lipid deposition (e.g., Lachnospiraceae and Collinsella) and increasing the abundance of beneficial bacteria (e.g., Ruminococcus and Turicibacter), thereby reducing hepatic lipogenesis and ultimately alleviates liver steatosis and lipid accumulation (Wang S

Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis