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Moreover, ROS can affect the overexpression of p53 and p21 cip1/waf1 , leading to the failure of DNA or apoptosis repair [49]

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Energy is produced at each stage of the process, and stepwise shortening of acyl-CoA generates one molecule of FADH 2 and NADH for every two-carbon unit released, while each acetyl-CoA molecule yields 3 molecules of NADH, 1 molecule of FADH 2 and 1 of GTP via the tricarboxylic acid cycle

ZS, as the corresponding author, contributed to the design of the review framework, provided critical revisions for important intellectual content, and supervised the entire project

Obesity, metabolic abnormality, and progression of CKD