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Some patients report passing stools more frequently than usual, whilst others notice changes primarily in consistency rather than frequency

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This distinction matters for treatment planning: dual therapy is most beneficial when insulin resistance, prediabetes, or metabolic syndrome are present alongside obesity

Regulatory safety review: FDA has identified serious adverse events including increased heart rate and systemic vasodilatory reaction, and has flagged concerns around immunogenicity, impurities, and limited data

3) initial decrease of IL-2 was significantly lower in ALS patients at the second visit compared to healthy controls