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Peptides were desalted using Waters Oasis HLB Elution Plate (30 M) according to the manufacturers instructions and sent for DUB identification and quantification using LC-MS/MS, as mentioned below

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It is important to understand that the key players evaluating their novel therapies in the pivotal and confirmatory trials should remain vigilant when selecting appropriate comparators to stand the greatest chance of a positive opinion from regulatory bodies, leading to approval, smooth launch, and rapid uptake

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