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Kojic acid targets specific areas of hyperpigmentation

A major worry is the possible increased risk of skin cancer and melanoma, since the peptides darken skin cells

doi: 10.1016/j.ejphar.2016.04.052 165 HolstJJBurcelinRNathansonE

Although the impact of GLP-1RAs on pancreatic cancer risk remains controversial, emerging evidence suggests that chronic low-grade inflammation and proliferative changes may constitute key pathophysiological mechanisms underlying pancreatic cancer development in patients receiving GLP-1RA therapy [8]