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Loneliness is Bad for your Health First of all, loneliness has a profound impact on physical health and mental well-being

Cigarette smokers are 2 to 4 times more likely to get heart disease than nonsmokers & smoking doubles a persons risk for a stroke

Furthermore, nicotine is not only significantly decreasing the testicular activity of androgenic enzymes including testicular steroidogenic acute regulatory (StAR) protein resulting in decreased intratesticular and plasma testosterone and gonadotropin concentrations, but also reduced the testicular levels of glutathione, activities of antioxidative enzymes and mitochondrial membrane potential in testicular cells

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Passive cigarette smoke exposure during various periods of life, genetic variants, and breast cancer risk among never smokers