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This patient's nausea is driven by the rapid concentration rise in the first 48 hours

Since IR governs the pathogenesis of NAFLD, the possible role of PIO in this setting gained special interest during the last two decades

Experimental procedures included surgery models such as subdiaphragmatic vagal deafferentation (SDA), specific ablation of the area postrema (AP), and paraventricular nucleus (PVN) lesions, all of which were conducted on Sprague-Dawley (SPDR) rats

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