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Binding of ,-disubstituted amino acids to arginase suggests new avenues for inhibitor design

In PC, pancreatic stellate cells form a dense stromal tissue, which is referred to as a desmoplastic reaction

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The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1

403,404 Alterations in gut microbiota can increase intestinal permeability, leading to the translocation of endotoxins and the activation of immune responses that contribute to peripheral nerve damage