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They suggested that some bacteria, such as Erysipelotrichi class, Allobaculum can induce a non-penetrable inner mucus, while other phyla, like TM7 and Proteobacteria have opposite effects [12]

The Phase 2a and 2b trials revealed a significant reduction of inflammatory and noninflammatory acne lesion counts following 12 weeks of topical OG at both 7.5% twice daily and 4.0% once daily.[2931] Topical OG is reportedly well tolerated with no serious treatment-related adverse events and may be an up-and-coming topical agent to treat oily skin

doi: 10.1172/jci.insight.175479 150 SakaiOUchidaTImaiHUetaT

Regulation of the activity of glucose-6-phosphate dehydrogenase by NADP+ and NADPH