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A study performed in primary cultures of OFs from GO patients and control subjects demonstrated that quercetin exerts an inhibitory effect on fibroblasts proliferation and HA release, with no difference between GO and control fibroblasts ( in vivo studies are needed to confirm this hypothesis, also considering that quercetin seems to act through necrosis, which may worsen autoimmunity against orbital antigens due to antigen exposure to the immune system

doi: 10.1016/j.transproceed.2008.10.009 56 HashimotoH.VertinoP

Patients with a history of allergic reactions to similar compounds or excipients present in the preserved formulation should exercise caution